At Dr. Irena Sandler's clinic, we administer NAD⁺ (nicotinamide adenine dinucleotide) infusions –
An essential molecule that serves as the basis for every energy production process in the body.
Over the years, NAD⁺ levels naturally decline, accelerating aging processes and impairing energy levels,
In the nervous system and the body's recovery ability.

Why is NAD⁺ so important?
• Responsible for optimal energy production in the mitochondria (the powerhouses of the cells).
• Affects brain health, concentration, mood, and memory.
• Inhibits aging processes by activating longevity-associated sirtuin proteins.
• Supports DNA repair and cell regeneration.
• Improves sleep quality, mood, and the ability to recover from physical or mental strain.

How is the treatment performed?
The treatment is administered via intravenous (IV) infusion of NAD⁺ or NADH at a controlled dosage, depending on medical needs and levels.
energy and the patient's health goals.
The protocol typically involves a series of 4 to 8 infusions, administered once every one to two weeks.
Close medical monitoring is maintained throughout the process, with the option to adjust dosages based on the body's response.
The goal is to achieve mitochondrial restoration, improvements in ATP, nervous system balance, and the restoration of energy.
Cellulose for the body.

Expected results
• Significant improvement in overall energy levels after just 2–3 treatments.
• Increased mental clarity and cognitive performance.
• Reduction in chronic fatigue and improved recovery after exertion.
• Support for brain fog, stress, or burnout.
• Contributes to improving sleep quality and mood.

Research data
• According to a study published in *Nature Aging* (2022), a decline in NAD⁺ levels is one of the prominent signs of
Cellular aging.
• Studies have shown that maintaining NAD⁺ levels improves mitochondrial function and extends cell lifespan by up to 30%.
Under experimental conditions.

• NAD⁺ therapy was found to reduce chronic fatigue and improve neurological markers in patients with injury.
Metabolic.
• A clinical trial (2021) demonstrated a 20–40% improvement in cognitive function following a series of NAD⁺ infusions.

Studies and Articles on NAD⁺
1. NAD⁺ metabolism and its roles in cellular processes during aging
Source: Nature Reviews Molecular Cell Biology (2022)
A comprehensive review article on the role of NAD⁺ in aging, energy, and mitochondrial processes.
Link: https://www.nature.com/articles/s41580-021-00441-9

2. NAD⁺ replenishment improves mitochondrial and stem cell function and extends lifespan in
mice
Source: Science (2016)
A study demonstrating improvement in mitochondrial function and cell survival following NAD⁺ administration.
Link: https://www.science.org/doi/10.1126/science.aaf2693

3. NAD⁺ augmentation restores age-related muscle dysfunction and mitochondrial
homeostasis
Source: Cell Metabolism (2018)
A study showing how NAD⁺ administration aids in muscle recovery and slows down aging processes.
Link: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(18)30237-4

4. Safety and efficacy of intravenous NAD⁺ infusions: a pilot study
Source: Frontiers in Aging Neuroscience (2020)
A clinical study that examined the safety of the infusions and their effect on energy levels and brain function.
Link: https://www.frontiersin.org/articles/10.3389/fnagi.2020.00064/full

Summary
NAD⁺ infusions are currently considered one of the most innovative and effective tools in the world of longevity.
They help restore energy, vitality, and optimal function to the body at the cellular level.
The treatment is performed solely under medical supervision, fully tailored to each patient.

At Dr Irena Sendler Longevity, we combine science, medicine, and a good life –

To enable you to live with clarity, energy, and optimal health over the long term.